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human SECISBP2 Adenovirus

Name 
Ad-h-SECISBP2
Cat No 
ADV-222510
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SECISBP2.

ADV-222510
Ad-h-SECISBP2

Ready-to-use Adenovirus expressing Human SECISBP2 (SECIS binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SBP2; Sec insertion sequence-binding protein 2; SECIS-binding protein 2; selenocysteine insertion sequence-binding protein 2
Description (eCommerce)
SECIS-binding protein 2 (SBP2) binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96T21].
Description (Vector)
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
Gene ID
79048
Gene Name (eCommerce)
SECIS binding protein 2
Gene Name (Vector)
SECIS binding protein 2
Gene Symbol
SECISBP2
HGNC ID
HGNC:30972
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2565
ORF Size (bp)
2565 bp
Protein Name (eCommerce)
Selenocysteine insertion sequence-binding protein 2
RefSeq ID
NM_024077
RefSeq Synonyms
NM_024077, NM_001282690, NM_001282689, NM_001282688, BC036109, BC001189,
Research Areas
Mitochondrion,mRNA Binding,RNA Binding,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SECIS-binding protein 2 (SBP2) binds to the SECIS element in the 3'-UTR of some mRNAs encoding selenoproteins. Binding is stimulated by SELB [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96T21].
UniGene ID
Hs.59804
UniProt ID (eCommerce)
Q96T21

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.