human SEC61B Adenovirus

Name 
Ad-h-SEC61B
Cat No 
ADV-222504
Availability
4-5 weeks

This is an Adenovirus expressing Human SEC61B.

ADV-222504
Ad-h-SEC61B

Ready-to-use Adenovirus expressing Human SEC61B (Sec61 translocon beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.
Gene ID
10952
Gene Name (Vector)
Sec61 translocon beta subunit
Gene Symbol
SEC61B
HGNC ID
HGNC:16993
ORF Size (aa)
291
RefSeq ID
NM_006808
RefSeq Synonyms
NM_006808, BC001734,
Species
human
UniGene ID
Hs.191887

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.