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human SCYL2 Adenovirus

Name 
Ad-h-SCYL2
Cat No 
ADV-222407
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SCYL2.

ADV-222407
Ad-h-SCYL2

Ready-to-use Adenovirus expressing Human SCYL2 (SCY1 like pseudokinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
coated vesicle-associated kinase of 104 kDa; CVAK104; SCY1-like 2; SCY1-like protein 2; SCY1-like, kinase-like 2
Description (eCommerce)
SCY1-like protein 2 (SCYL2) is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. SCYL2 may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6P3W7].
Gene ID
55681
Gene Name (eCommerce)
SCY1 like pseudokinase 2
Gene Name (Vector)
SCY1 like pseudokinase 2
Gene Symbol
SCYL2
HGNC ID
HGNC:19286
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2790
ORF Size (bp)
2790 bp
Protein Name (eCommerce)
SCY1-like protein 2
RefSeq ID
NM_017988
RefSeq Synonyms
NM_017988, NM_001330256, NM_001330254, NM_001330253, NM_001317784, BC063798,
Research Areas
Golgi Apparatus,Kinase/Phosphatase,Lysosomal Transport,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
SCY1-like protein 2 (SCYL2) is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. SCYL2 may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6P3W7].
UniGene ID
Hs.506481
UniProt ID (eCommerce)
Q6P3W7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.