human SAP30 Adenovirus

Name 
Ad-h-SAP30
Cat No 
ADV-222235
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SAP30.

ADV-222235
Ad-h-SAP30

Ready-to-use Adenovirus expressing Human SAP30 (Sin3A associated protein 30). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
30 kDa Sin3-associated polypeptide; histone deacetylase complex subunit SAP30; Sin3 corepressor complex subunit SAP30; Sin3A-associated protein, 30kDa; sin3-associated polypeptide p30; sin3-associated polypeptide, 30 kDa; Sin3-associated polypeptide, 30kDa
Description (eCommerce)
Sin3A-associated protein 30kDa (SAP30) is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones [taken from NCBI Entrez Gene (Gene ID: 8819)].
Description (Vector)
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Gene ID
8819
Gene Name (eCommerce)
Sin3A associated protein 30
Gene Name (Vector)
Sin3A associated protein 30
Gene Symbol
SAP30
HGNC ID
HGNC:10532
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
663
ORF Size (bp)
663 bp
Protein Name (eCommerce)
Histone deacetylase complex subunit SAP30
RefSeq ID
NM_003864
RefSeq Synonyms
NM_003864, BC016757,
Research Areas
Epigenetic Regulation of Gene Expression,Hedgehog Signaling,Notch Signaling,Signal Transduction,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
signal_transduction,cell_biology,transcription_translation,developmental_biology,signal_transduction,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Sin3A-associated protein 30kDa (SAP30) is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones [taken from NCBI Entrez Gene (Gene ID: 8819)].
UniGene ID
Hs.591715
UniProt ID (eCommerce)
O75446

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.