human RYK Adenovirus
This is an Adenovirus expressing Human RYK.
ADV-222152
Ad-h-RYK
Ready-to-use Adenovirus expressing Human RYK (receptor-like tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D3S3195; JTK5; JTK5A; RYK1
Description (Vector)
RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
6259
Gene Name (Vector)
receptor-like tyrosine kinase
Gene Symbol
RYK
HGNC ID
HGNC:10481
ORF Size (aa)
1833
ORF Size (bp)
1833 bp
RefSeq ID
NM_002958
RefSeq Synonyms
NM_002958, NM_001005861, BC153090, BC148614,
Species
human
UniGene ID
Hs.654562
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.