human RREB1 Adenovirus

Name 
Ad-h-RREB1
Cat No 
ADV-221998
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RREB1.

ADV-221998
Ad-h-RREB1

Ready-to-use Adenovirus expressing Human RREB1 (ras responsive element binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DNA-binding protein; FINB; finger protein in nuclear bodies; hindsight homolog; HNT; LZ321; raf-responsive zinc finger protein LZ321; ras-responsive element-binding protein 1; RREB-1; Zep-1; zinc finger motif enhancer-binding protein 1
Description (eCommerce)
Ras-responsive element-binding protein 1 (RREB1) is a transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. RREB1 may be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. REBB1 represses the angiotensinogen gene and negatively regulates the transcriptional activity of AR [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92766].
Description (Vector)
RREB1 is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene.
Gene ID
6239
Gene Name (eCommerce)
ras responsive element binding protein 1
Gene Name (Vector)
ras responsive element binding protein 1
Gene Symbol
RREB1
HGNC ID
HGNC:10449
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5064
ORF Size (bp)
5064 bp
Protein Name (eCommerce)
Ras-responsive element-binding protein 1
RefSeq ID
NM_001003698
RefSeq Synonyms
NM_001168344, NM_001003700, NM_001003699, NM_001003698, BC172432,
Research Areas
Signal Transduction,Transcription Factor/Regulator,Transport,Zinc-finger
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Ras-responsive element-binding protein 1 (RREB1) is a transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. RREB1 may be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. REBB1 represses the angiotensinogen gene and negatively regulates the transcriptional activity of AR [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q92766].
UniGene ID
Hs.298248
UniProt ID (eCommerce)
Q92766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.