human RRBP1 Adenovirus

Name 
Ad-h-RRBP1
Cat No 
ADV-221996
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RRBP1.

ADV-221996
Ad-h-RRBP1

Ready-to-use Adenovirus expressing Human RRBP1 (ribosome binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
180 kDa ribosome receptor homolog; ES/130; ES/130-related protein; ES130; hES; ribosome binding protein 1 homolog 180kDa (dog); ribosome receptor protein; ribosome-binding protein 1; RRp
Description (eCommerce)
Ribosome binding protein 1 (RRBP1) is a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this protein plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions [taken from NCBI Entrez Gene (Gene ID: 6238)].
Description (Vector)
RRBP1 encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
Gene ID
6238
Gene Name (eCommerce)
ribosome binding protein 1
Gene Name (Vector)
ribosome binding protein 1
Gene Symbol
RRBP1
HGNC ID
HGNC:10448
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2805
ORF Size (bp)
2805 bp
Protein Name (eCommerce)
Ribosome-binding protein 1
RefSeq ID
NM_004587
RefSeq Synonyms
NM_004587, NM_001042576, BC128578, BC128577,
Research Areas
Signal Transduction,Translational Control,Transport
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Ribosome binding protein 1 (RRBP1) is a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this protein plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions [taken from NCBI Entrez Gene (Gene ID: 6238)].
UniGene ID
Hs.472213
UniProt ID (eCommerce)
Q9P2E9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.