human RASA3 Adenovirus

Name 
Ad-h-RASA3
Cat No 
ADV-220760
Availability
4-5 weeks

This is an Adenovirus expressing Human RASA3.

ADV-220760
Ad-h-RASA3

Ready-to-use Adenovirus expressing Human RASA3 (RAS p21 protein activator 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GAP1IP4BP; GAPIII
Description (Vector)
RASA3 is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Gene ID
22821
Gene Name (Vector)
RAS p21 protein activator 3
Gene Symbol
RASA3
HGNC ID
HGNC:20331
ORF Size (aa)
2505
ORF Size (bp)
2505 bp
RefSeq ID
NM_007368
RefSeq Synonyms
NM_007368, NM_001320822, NM_001320821, BC047242, BC038456,
Species
human
UniGene ID
Hs.593075

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.