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human RAPH1 Adenovirus

Name 
Ad-h-RAPH1
Cat No 
ADV-220743
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RAPH1.

ADV-220743
Ad-h-RAPH1

Ready-to-use Adenovirus expressing Human RAPH1 (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ALS2CR18; ALS2CR9; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein; lamellipodin; LPD; PREL2; PREL-2; proline-rich EVH1 ligand 2; Protein RMO1; RalGDS/AF-6; RAPH1; ras-associated and pleckstrin homology domains-containing protein 1; RMO1
Description (eCommerce)
RAPH1 is a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. RAPH1 regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly [taken from NCBI Entrez Gene (Gene ID: 65059)].
Gene ID
65059
Gene Name (eCommerce)
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Gene Name (Vector)
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Gene Symbol
RAPH1
HGNC ID
HGNC:14436
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3753
ORF Size (bp)
3753 bp
Protein Name (eCommerce)
Ras-associated and pleckstrin homology domains-containing protein 1
RefSeq ID
NM_213589
RefSeq Synonyms
NM_213589, NM_203365, NM_001329728, BC156922, BC156182,
Research Areas
Cytoskeleton,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
RAPH1 is a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. RAPH1 regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly [taken from NCBI Entrez Gene (Gene ID: 65059)].
UniGene ID
Hs.471162
UniProt ID (eCommerce)
Q70E73

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.