human RANBP3 Adenovirus

Name 
Ad-h-RANBP3
Cat No 
ADV-220705
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RANBP3.

ADV-220705
Ad-h-RANBP3

Ready-to-use Adenovirus expressing Human RANBP3 (RAN binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; ran-binding protein 3; RanBP3
Description (eCommerce)
Ran binding protein 3 (RanBP3) is a Ran (ras-related nuclear protein) binding protein and a component of a nuclear transport complex that functions to export proteins out of the nucleus. RanBP3 binds the nucleocytoplasmic transport receptor, CRM1, and facilitates the export of CRM1 substrates. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.
Description (Vector)
RANBP3 encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
8498
Gene Name (eCommerce)
RAN binding protein 3
Gene Name (Vector)
RAN binding protein 3
Gene Symbol
RANBP3
HGNC ID
HGNC:9850
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
Protein Name (eCommerce)
Ran-binding protein 3
RefSeq ID
NM_003624
RefSeq Synonyms
NM_007322, NM_007320, NM_003624, NM_001300865, BC004349,
Research Areas
Host-Virus Interactions,Signal Transduction,Transport,Wnt Signaling
Research Areas (Faceted)
cell_biology,infectious_disease,signal_transduction
Species
human
Target Sentence
Ran binding protein 3 (RanBP3) is a Ran (ras-related nuclear protein) binding protein and a component of a nuclear transport complex that functions to export proteins out of the nucleus. RanBP3 binds the nucleocytoplasmic transport receptor, CRM1, and facilitates the export of CRM1 substrates. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.
UniGene ID
Hs.531752
UniProt ID (eCommerce)
Q9H6Z4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.