human RABGEF1 Adenovirus
This is an Adenovirus expressing Human RABGEF1.
ADV-220608
Ad-h-RABGEF1
Ready-to-use Adenovirus expressing Human RABGEF1 (RAB guanine nucleotide exchange factor (GEF) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RAB guanine nucleotide exchange factor (GEF) 1; rab5 GDP/GTP exchange factor; rabaptin-5-associated exchange factor for Rab5; RABEX5; rabex-5; RAP1
Description (eCommerce)
RabGEF1 (Rab guanine nucleotide exchange factor 1) is a rab effector protein acting as linker between gamma-adaptin, Rab4A or Rab5A. RabGEF1 is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. It stimulates nucleotide exchange on Rab5A. RabGEF1 can act as a ubiquitin ligase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UJ41].
Description (Vector)
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 (PubMed 9323142)).(supplied by OMIM, Mar 2010)
Gene ID
27342
Gene Name (eCommerce)
RAB guanine nucleotide exchange factor 1
Gene Name (Vector)
RAB guanine nucleotide exchange factor (GEF) 1
Gene Symbol
RABGEF1
HGNC ID
HGNC:17676
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1476
ORF Size (bp)
1476 bp
Protein Name (eCommerce)
Rab5 GDP/GTP exchange factor
RefSeq ID
NM_014504
RefSeq Synonyms
NM_014504, NM_001287062, NM_001287061, NM_001287060, BC015330,
Research Areas
Transport,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
RabGEF1 (Rab guanine nucleotide exchange factor 1) is a rab effector protein acting as linker between gamma-adaptin, Rab4A or Rab5A. RabGEF1 is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. It stimulates nucleotide exchange on Rab5A. RabGEF1 can act as a ubiquitin ligase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UJ41].
UniGene ID
Hs.530053
UniProt ID (eCommerce)
Q9UJ41
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.