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human PTPRO Adenovirus

Name 
Ad-h-PTPRO
Cat No 
ADV-220357
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PTPRO.

ADV-220357
Ad-h-PTPRO

Ready-to-use Adenovirus expressing Human PTPRO (protein tyrosine phosphatase, receptor type O). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
Description (Vector)
PTPRO encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. PTPRO contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. PTPRO is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
Gene ID
5800
Gene Name (Vector)
protein tyrosine phosphatase, receptor type O
Gene Symbol
PTPRO
HGNC ID
HGNC:9678
ORF Size (aa)
3651
ORF Size (bp)
3651 bp
RefSeq ID
NM_002848
RefSeq Synonyms
NM_030671, NM_030670, NM_030669, NM_030668, NM_030667, NM_002848, BC126203, BC126201, BC035960,
Species
human
UniGene ID
Hs.160871

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.