human PTPRB Adenovirus
This is an Adenovirus expressing Human PTPRB.
ADV-220334
Ad-h-PTPRB
Ready-to-use Adenovirus expressing Human PTPRB (protein tyrosine phosphatase, receptor type B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPTP-BETA; HPTPB; PTPB; R-PTP-BETA; VEPTP
Description (Vector)
PTPRB is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.
Gene ID
5787
Gene Name (Vector)
protein tyrosine phosphatase, receptor type B
Gene Symbol
PTPRB
HGNC ID
HGNC:9665
ORF Size (aa)
5994
ORF Size (bp)
5994 bp
RefSeq ID
NM_002837
RefSeq Synonyms
NM_002837, NM_001330204, NM_001206972, NM_001206971, NM_001109754, BC143360, BC143356, BC113463, BC101679, BC051329,
Species
human
UniGene ID
Hs.434375
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.