human PRKAA2 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-219832
Availability:
3-5 weeks
Name:
Ad-h-PRKAA2
This is an Adenovirus expressing Human PRKAA2.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PRKAA2
- Gene Name
- protein kinase AMP-activated catalytic subunit alpha 2
- Gene ID
- 5563
- Gene Synonyms
- AMPK; AMPK2; AMPKa2; PRKAA
- ORF Size
- 1659 bp
- RefSeq#
- BC069680
- Gene Description
- PRKAA2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- UniGene ID
- Hs.437039
- HGNC ID
- HGNC:9377
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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