human POLR1D Adenovirus

Name 
Ad-h-POLR1D
Cat No 
ADV-219382
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human POLR1D.

ADV-219382
Ad-h-POLR1D

Ready-to-use Adenovirus expressing Human POLR1D (RNA polymerase I subunit D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AC19; DNA-directed RNA polymerase I subunit D; DNA-directed RNA polymerases I and III subunit RPAC2; hRPA19; POLR1C; polymerase (RNA) I polypeptide D, 16kDa; polymerase (RNA) I subunit D; Protein POLR1D; RNA polymerase I 16 kDa subunit; RNA polymerase I subunit D; RNA polymerases I and III subunit AC2; RPA16; RPA9; RPAC2; RPC16; RPO1-3; TCS2
Description (eCommerce)
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in the POLR1D gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder [taken from NCBI Entrez Gene (Gene ID: 51082)].
Description (Vector)
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
Gene ID
51082
Gene Name (eCommerce)
RNA polymerase I and III subunit D
Gene Name (Vector)
RNA polymerase I subunit D
Gene Symbol
POLR1D
HGNC ID
HGNC:20422
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
402
Protein Name (eCommerce)
DNA-directed RNA polymerases I and III subunit RPAC2;Protein POLR1D, isoform 2
RefSeq ID
NM_015972
RefSeq Synonyms
NM_152705, NM_015972, NM_001206559, BC018528, BC015319, BC000889,
Research Areas
Cancer,Epigenetic Regulation of Gene Expression,Gene Expression,Host-Virus Interactions,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cancer,cell_biology,genetics,infectious_disease,signal_transduction
Species
human
Target Sentence
POLR1D is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in the POLR1D gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder [taken from NCBI Entrez Gene (Gene ID: 51082)].
UniGene ID
Hs.507584
UniProt ID (eCommerce)
P0DPB6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.