human PHYH Adenovirus

Name
Ad-h-PHYH

Cat No
ADV-218866

Availability
4-5 weeks

This is an Adenovirus expressing Human PHYH.

ADV-218866

Ad-h-PHYH

Ready-to-use Adenovirus expressing Human PHYH (phytanoyl-CoA 2-hydroxylase). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

LN1; LNAP1; PAHX; PHYH1; RD

Description (Vector)

PHYH is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene ID

5264

Gene Name (Vector)

phytanoyl-CoA 2-hydroxylase

Gene Symbol

PHYH

HGNC ID

HGNC:8940

ORF Size (aa)

1017

ORF Size (bp)

1017 bp

RefSeq ID

NM_006214

RefSeq Synonyms

NM_006214, NM_001323084, NM_001323083, NM_001323082, NM_001323080, NM_001037537, BC029512,

Species

human

UniGene ID

Hs.498732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.