human PDX1 Adenovirus
This is an Adenovirus expressing Human PDX1.
ADV-218559
Ad-h-PDX1
Ready-to-use Adenovirus expressing Human PDX1 (pancreatic and duodenal homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Description (Vector)
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Gene ID
3651
Gene Name (Vector)
pancreatic and duodenal homeobox 1
Gene Symbol
PDX1
HGNC ID
HGNC:6107
ORF Size (aa)
852
RefSeq ID
NM_000209
RefSeq Synonyms
NM_000209, BC111592,
Species
human
UniGene ID
Hs.32938
Related Citations
- Spheroid Fabrication Using Concave Microwells Enhances the Differentiation Efficacy and Function of Insulin-Producing Cells via Cytoskeletal Changes. YN Lee, etc, (2020), Cells
- Enhanced insulin production and reprogramming efficiency of mesenchymal stem cells derived from porcine pancreas using suitable induction medium. S Lee, S, (2018), Xenotransplantation
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.