human PDE1A Adenovirus

Name 
Ad-h-PDE1A
Cat No 
ADV-218461
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PDE1A.

ADV-218461
Ad-h-PDE1A

Ready-to-use Adenovirus expressing Human PDE1A (phosphodiesterase 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
Description (Vector)
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 (PubMed 11342109); Fidock et al., 2002 (PubMed 11747989)).(supplied by OMIM, Oct 2009)
Gene ID
5136
Gene Name (Vector)
phosphodiesterase 1A
Gene Symbol
PDE1A
HGNC ID
HGNC:8774
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
RefSeq ID
NM_001003683
RefSeq Synonyms
NM_005019, NM_001258314, NM_001258313, NM_001258312, NM_001003683, BC022480,
Species
human
UniGene ID
Hs.680373

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.