human PCSK2 Adenovirus
This is an Adenovirus expressing Human PCSK2.
ADV-218410
Ad-h-PCSK2
Ready-to-use Adenovirus expressing Human PCSK2 (proprotein convertase subtilisin/kexin type 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NEC 2; NEC-2; NEC2; PC2; SPC2
Description (Vector)
PCSK2 encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. PCSK2 may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5126
Gene Name (Vector)
proprotein convertase subtilisin/kexin type 2
Gene Symbol
PCSK2
HGNC ID
HGNC:8744
ORF Size (aa)
1860
ORF Size (bp)
1860 bp
RefSeq ID
NM_002594
RefSeq Synonyms
NM_002594, NM_001201529, NM_001201528, BC040546, BC005815,
Species
human
UniGene ID
Hs.315186
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.