human PATZ1 Adenovirus
This is an Adenovirus expressing Human PATZ1.
ADV-218266
Ad-h-PATZ1
Ready-to-use Adenovirus expressing Human PATZ1 (POZ/BTB and AT hook containing zinc finger 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
Description (Vector)
PATZ1 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
Gene ID
23598
Gene Name (Vector)
POZ/BTB and AT hook containing zinc finger 1
Gene Symbol
PATZ1
HGNC ID
HGNC:13071
ORF Size (aa)
1614
ORF Size (bp)
1614 bp
RefSeq ID
NM_014323
RefSeq Synonyms
NM_032052, NM_032051, NM_032050, NM_014323, BC021091,
Species
human
UniGene ID
Hs.517557
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.