human OGDH Adenovirus

Name
Ad-h-OGDH

Cat No
ADV-217373

Availability
4-5 weeks

This is an Adenovirus expressing Human OGDH.

ADV-217373

Ad-h-OGDH

Ready-to-use Adenovirus expressing Human OGDH (oxoglutarate dehydrogenase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AKGDH; E1k; OGDC

Description (Vector)

OGDH encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

4967

Gene Name (Vector)

oxoglutarate dehydrogenase

Gene Symbol

OGDH

HGNC ID

HGNC:8124

ORF Size (aa)

3072

ORF Size (bp)

3072 bp

RefSeq ID

NM_002541

RefSeq Synonyms

NM_002541, NM_001165036, NM_001003941, BC014617, BC004964,

Species

human

UniGene ID

Hs.488181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.