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human NUP85 Adenovirus

Name 
Ad-h-NUP85
Cat No 
ADV-217261
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human NUP85.

ADV-217261
Ad-h-NUP85

Ready-to-use Adenovirus expressing Human NUP85 (nucleoporin 85). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
85 kDa nucleoporin; FROUNT; nuclear pore complex protein Nup85; nucleoporin 85kDa; nucleoporin Nup75; nucleoporin Nup85; Nup75; Pericentrin-1
Description (eCommerce)
Nucleoporin 85 (NUP85) is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex, it plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2 and seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW27].
Description (Vector)
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP85 is part of one such subcomplex, Nup107-160.
Gene ID
79902
Gene Name (eCommerce)
nucleoporin 85
Gene Name (Vector)
nucleoporin 85
Gene Symbol
NUP85
HGNC ID
HGNC:8734
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1971
ORF Size (bp)
1971 bp
Protein Name (eCommerce)
Nuclear pore complex protein Nup85
RefSeq ID
NM_024844
RefSeq Synonyms
NM_024844, NM_001330472, NM_001303276, BC000697,
Research Areas
Breast Cancer,Cancer,Cell Cycle,Cell Division,Cytoskeleton,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,mRNA Processing,mRNA Transport,Ribonucleoprotein Transport,RNA Processing,RNA Transport,Transport
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Nucleoporin 85 (NUP85) is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex, it plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2 and seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW27].
UniGene ID
Hs.362817
UniProt ID (eCommerce)
Q9BW27

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.