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human NUP133 Adenovirus

Name 
Ad-h-NUP133
Cat No 
ADV-217233
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human NUP133.

ADV-217233
Ad-h-NUP133

Ready-to-use Adenovirus expressing Human NUP133 (nucleoporin 133). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
133 kDa nucleoporin; hNUP133; nuclear pore complex protein Nup133; nucleoporin 133kD; nucleoporin 133kDa; nucleoporin Nup133
Description (eCommerce)
The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nucleoporin 133 kDa (NUP133) has been shown to play a role in mRNA export.
Description (Vector)
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.
Gene ID
55746
Gene Name (eCommerce)
nucleoporin 133
Gene Name (Vector)
nucleoporin 133
Gene Symbol
NUP133
HGNC ID
HGNC:18016
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3471
ORF Size (bp)
3471 bp
Protein Name (eCommerce)
Nuclear pore complex protein Nup133
RefSeq ID
NM_018230
RefSeq Synonyms
NM_018230, BC020107,
Research Areas
Cell Cycle,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,mRNA Processing,mRNA Transport,Nuclear Import/Export,Ribonucleoprotein Transport,RNA Processing,RNA Transport,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism
Species
human
Target Sentence
The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nucleoporin 133 kDa (NUP133) has been shown to play a role in mRNA export.
UniGene ID
Hs.12457
UniProt ID (eCommerce)
Q8WUM0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.