human MYOM1 Adenovirus
This is an Adenovirus expressing Human MYOM1.
ADV-216231
Ad-h-MYOM1
Ready-to-use Adenovirus expressing Human MYOM1 (myomesin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SKELEMIN
Description (Vector)
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
8736
Gene Name (Vector)
myomesin 1
Gene Symbol
MYOM1
HGNC ID
HGNC:7613
ORF Size (aa)
4770
ORF Size (bp)
4770 bp
RefSeq ID
NM_003803
RefSeq Synonyms
NM_019856, NM_003803, BC116183,
Species
human
UniGene ID
Hs.464469
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.