human MCM3AP Adenovirus

Name 
Ad-h-MCM3AP
Cat No 
ADV-215183
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MCM3AP.

ADV-215183
Ad-h-MCM3AP

Ready-to-use Adenovirus expressing Human MCM3AP (minichromosome maintenance complex component 3 associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
80 kDa MCM3-associated protein; GANP; germinal center-associated nuclear protein; germinal-center associated nuclear protein; germinal-centre associated nuclear protein; MAP80; MCM3 acetylating protein; MCM3 acetyltransferase; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; MCM3AP; PNRIID; SAC3
Description (eCommerce)
Germinal center –associated nuclear protein (GANP) has domains for MCM3-binding and RNA-primase activities. GANP has recently been reported to be transcribed from the same locus as MCM3AP.
Description (Vector)
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
Gene ID
8888
Gene Name (eCommerce)
minichromosome maintenance complex component 3 associated protein
Gene Name (Vector)
minichromosome maintenance complex component 3 associated protein
Gene Symbol
MCM3AP
HGNC ID
HGNC:6946
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5943
ORF Size (bp)
5943 bp
Protein Name (eCommerce)
Germinal-center associated nuclear protein
RefSeq ID
NM_003906
RefSeq Synonyms
NM_003906, BC104960, BC104958,
Research Areas
Acyltransferase,Cell Cycle,DNA Replication,Immunology,mRNA transport,Replication,RNA Transport,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,immunology,genetics
Species
human
Target Sentence
Germinal center –associated nuclear protein (GANP) has domains for MCM3-binding and RNA-primase activities. GANP has recently been reported to be transcribed from the same locus as MCM3AP.
UniGene ID
Hs.389037
UniProt ID (eCommerce)
O60318

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.