human LRRFIP1 Adenovirus

Name
Ad-h-LRRFIP1

Cat No
ADV-214599

Availability
4-5 weeks

This is an Adenovirus expressing Human LRRFIP1.

ADV-214599

Ad-h-LRRFIP1

Ready-to-use Adenovirus expressing Human LRRFIP1 (LRR binding FLII interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

FLAP1; FLAP-1; FLIIAP1; GC-binding factor 2; GCF2; GCF-2; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP

Description (eCommerce)

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP1 may control smooth muscle cell proliferation following artery injury through PDGFA repression. LRRFIP1 May also bind double-stranded RNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q32MZ4].

Gene ID

9208

Gene Name (eCommerce)

LRR binding FLII interacting protein 1

Gene Name (Vector)

LRR binding FLII interacting protein 1

Gene Symbol

LRRFIP1

HGNC ID

HGNC:6702

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2259

ORF Size (bp)

2259 bp

Protein Name (eCommerce)

Leucine-rich repeat flightless-interacting protein 1

RefSeq ID

NM_004735

RefSeq Synonyms

NM_004735, NM_001137553, NM_001137552, NM_001137551, NM_001137550, BC108914, BC108913, BC010662,

Research Areas

Cytoskeleton,FGF Signaling,Immunology,Innate Immunity,RNA Binding,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP1 may control smooth muscle cell proliferation following artery injury through PDGFA repression. LRRFIP1 May also bind double-stranded RNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q32MZ4].

UniGene ID

Hs.471779

UniProt ID (eCommerce)

Q32MZ4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.