human LRRC16A Adenovirus

Name 
Ad-h-LRRC16A
Cat No 
ADV-214522
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LRRC16A.

ADV-214522
Ad-h-LRRC16A

Ready-to-use Adenovirus expressing Human CARMIL1 (capping protein regulator and myosin 1 linker 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
capping protein regulator and myosin 1 linker protein 1; capping protein, Arp2/3 and myosin-I linker homolog 1; capping protein, Arp2/3 and myosin-I linker protein 1; capping protein, Arp2/3, and Myosin-I Linker homolog 1; CARMIL; CARMIL homolog; CARMIL1a; dJ501N12.1; dJ501N12.5; F-actin-uncapping protein LRRC16A; leucine rich repeat containing 16; leucine rich repeat containing 16A; leucine-rich repeat-containing protein 16A; LRRC16; LRRC16A; testicular tissue protein Li 107
Description (eCommerce)
CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5VZK9].
Gene ID
55604
Gene Name (eCommerce)
capping protein regulator and myosin 1 linker 1
Gene Name (Vector)
capping protein regulator and myosin 1 linker 1
Gene Symbol
CARMIL1
HGNC ID
HGNC:21581
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4098
ORF Size (bp)
4098 bp
Protein Name (eCommerce)
F-actin-uncapping protein LRRC16A
RefSeq ID
NM_017640
RefSeq Synonyms
NM_017640, NM_001173977, BC172573, BC172272, BC140770,
Research Areas
Cell Biology,Metabolism/Metabolic Process,Ubiquitination
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
CARMIL binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. It increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. CARMIL Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).CARMIL may control actin dynamics in lamellipodi and be required for cell migration [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5VZK9].
UniGene ID
Hs.670507
UniProt ID (eCommerce)
Q5VZK9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.