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human PILRB Adenovirus

Name 
Ad-h-PILRB
Cat No 
ADV-214101
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PILRB.

ADV-214101
Ad-h-PILRB

Ready-to-use Adenovirus expressing Human PILRB (paired immunoglobin-like type 2 receptor beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FDFACT1; FDFACT2
Description (Vector)
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner, and functions in the activating role. Alternatively spliced transcript variants have been noted for this gene, but the full-length nature of many is not known.
Gene ID
29990
Gene Name (Vector)
paired immunoglobin-like type 2 receptor beta
Gene Symbol
PILRB
HGNC ID
HGNC:18297
ORF Size (aa)
684
ORF Size (bp)
684 bp
RefSeq ID
NM_178238
RefSeq Synonyms
NM_178238, BC050547,
Species
human
UniGene ID
Hs.632314

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.