human KLF12 Adenovirus

Name 
Ad-h-KLF12
Cat No 
ADV-213178
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human KLF12.

ADV-213178
Ad-h-KLF12

Ready-to-use Adenovirus expressing Human KLF12 (Kruppel like factor 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AP-2 repressor; AP2REP; AP-2rep; AP-2rep transcription factor; HSPC122; KLF12 zinc finger transcriptional repressor; Krueppel-like factor 12; transcriptional repressor AP-2rep
Description (eCommerce)
Krueppel-like factor 12 (KLF12) confers strong transcriptional repression to the AP-2-alpha gene. KLF12 binds to a regulatory element (A32) in the AP-2-alpha gene promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y4X4].
Description (Vector)
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
11278
Gene Name (eCommerce)
Kruppel like factor 12
Gene Name (Vector)
Kruppel like factor 12
Gene Symbol
KLF12
HGNC ID
HGNC:6346
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1209
ORF Size (bp)
1209 bp
Protein Name (eCommerce)
Krueppel-like factor 12
RefSeq ID
NM_007249
RefSeq Synonyms
NM_007249, BC019680,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Krueppel-like factor 12 (KLF12) confers strong transcriptional repression to the AP-2-alpha gene. KLF12 binds to a regulatory element (A32) in the AP-2-alpha gene promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y4X4].
UniGene ID
Hs.592500
UniProt ID (eCommerce)
Q9Y4X4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.