human KIF23 Adenovirus

Name 
Ad-h-KIF23
Cat No 
ADV-213089
Availability
4-5 weeks

This is an Adenovirus expressing Human KIF23.

ADV-213089
Ad-h-KIF23

Ready-to-use Adenovirus expressing Human KIF23 (kinesin family member 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CHO1; kinesin-like 5 (mitotic kinesin-like protein 1); Kinesin-like protein 5; kinesin-like protein KIF23; KNSL5; Mitotic kinesin-like protein 1; MKLP1; MKLP-1
Description (eCommerce)
Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MKLP1 has been demonstrated to cross-bridge anti-parallel microtubules and drive microtubule movements.
Description (Vector)
KIF23 is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in two transcript variants encoding two different isoforms.
Gene ID
9493
Gene Name (eCommerce)
kinesin family member 23
Gene Name (Vector)
kinesin family member 23
Gene Symbol
KIF23
HGNC ID
HGNC:6392
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2571
ORF Size (bp)
2571 bp
Protein Name (eCommerce)
Kinesin-like protein KIF23
RefSeq ID
NM_004856
RefSeq Synonyms
NM_138555, NM_004856, NM_001281301, BC051826,
Research Areas
Antigen Processing and Presentation,Cancer,Cell Cycle,Cell Division,Cytoskeleton,Immunology,MicroRNAs in Cancer,Signal Transduction
Research Areas (Faceted)
cancer,genetics,signal_transduction,immunology,cell_biology,cell_cycle
Species
human
Target Sentence
Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MKLP1 has been demonstrated to cross-bridge anti-parallel microtubules and drive microtubule movements.
UniGene ID
Hs.270845
UniProt ID (eCommerce)
Q02241

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.