human KIF20A Adenovirus

Name 
Ad-h-KIF20A
Cat No 
ADV-213083
Availability
4-5 weeks

This is an Adenovirus expressing Human KIF20A.

ADV-213083
Ad-h-KIF20A

Ready-to-use Adenovirus expressing Human KIF20A (kinesin family member 20A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GG10_2; kinesin-like protein KIF20A; mitotic kinesin-like protein 2; MKLP2; RAB6 interacting, kinesin-like (rabkinesin6); rab6-interacting kinesin-like protein; RAB6KIFL; rabkinesin-6
Description (eCommerce)
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF20A/RAB6KIFL plays a role in transport within the golgi via interaction with Rab6 small GTPase as well as in mitosis and cytokinesis where it localizes to the spindle in anaphase and cleavage furrow and midbody in telophase.
Gene ID
10112
Gene Name (eCommerce)
kinesin family member 20A
Gene Name (Vector)
kinesin family member 20A
Gene Symbol
KIF20A
HGNC ID
HGNC:9787
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2673
ORF Size (bp)
2673 bp
Protein Name (eCommerce)
Kinesin-like protein KIF20A
RefSeq ID
NM_005733
RefSeq Synonyms
NM_005733, BC012999,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Golgi Apparatus,PLK1 Signaling,Signal Transduction,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF20A/RAB6KIFL plays a role in transport within the golgi via interaction with Rab6 small GTPase as well as in mitosis and cytokinesis where it localizes to the spindle in anaphase and cleavage furrow and midbody in telophase.
UniGene ID
Hs.718626
UniProt ID (eCommerce)
O95235

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.