human KIAA0427 Adenovirus
This is an Adenovirus expressing Human KIAA0427.
ADV-212914
Ad-h-KIAA0427
Ready-to-use Adenovirus expressing Human CTIF (cap binding complex dependent translation initiation factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gm672; KIAA0427
Description (Vector)
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 (PubMed 19648179)).(supplied by OMIM, Dec 2009)
Gene ID
9811
Gene Name (Vector)
cap binding complex dependent translation initiation factor
Gene Symbol
CTIF
HGNC ID
HGNC:23925
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
RefSeq ID
NM_014772
RefSeq Synonyms
NM_014772, NM_001142397, BC042146,
Species
human
UniGene ID
Hs.145230
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.