human KCNQ3 Adenovirus
This is an Adenovirus expressing Human KCNQ3.
ADV-212773
Ad-h-KCNQ3
Ready-to-use Adenovirus expressing Human KCNQ3 (potassium voltage-gated channel subfamily Q member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BFNC2; EBN2; KV7.3
Description (Vector)
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found.
Gene ID
3786
Gene Name (Vector)
potassium voltage-gated channel subfamily Q member 3
Gene Symbol
KCNQ3
HGNC ID
HGNC:6297
ORF Size (aa)
2616
ORF Size (bp)
2616 bp
RefSeq ID
NM_004519
RefSeq Synonyms
NM_004519, NM_001204824, BC152755,
Species
human
UniGene ID
Hs.374023
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.