human KCNN1 Adenovirus
This is an Adenovirus expressing Human KCNN1.
ADV-212765
Ad-h-KCNN1
Ready-to-use Adenovirus expressing Human KCNN1 (potassium calcium-activated channel subfamily N member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hSK1; KCa2.1; SK1; SKCA1
Description (Vector)
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.
Gene ID
3780
Gene Name (Vector)
potassium calcium-activated channel subfamily N member 1
Gene Symbol
KCNN1
HGNC ID
HGNC:6290
ORF Size (aa)
1632
ORF Size (bp)
1632 bp
RefSeq ID
NM_002248
RefSeq Synonyms
NM_002248, BC075037,
Species
human
UniGene ID
Hs.158173
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.