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human KCNH1 Adenovirus

Name 
Ad-h-KCNH1
Cat No 
ADV-212695
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human KCNH1.

ADV-212695
Ad-h-KCNH1

Ready-to-use Adenovirus expressing Human KCNH1 (potassium voltage-gated channel subfamily H member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EAG; EAG1; h-eag; hEAG1; Kv10.1; TMBTS; ZLS1
Description (Vector)
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
Gene ID
3756
Gene Name (Vector)
potassium voltage-gated channel subfamily H member 1
Gene Symbol
KCNH1
HGNC ID
HGNC:6250
ORF Size (aa)
2889
ORF Size (bp)
2889 bp
RefSeq ID
NM_002238
RefSeq Synonyms
NM_172362, NM_002238, BC143599, BC113709,
Species
human
UniGene ID
Hs.553187

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.