human KARS Adenovirus

Name 
Ad-h-KARS
Cat No 
ADV-212623
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human KARS.

ADV-212623
Ad-h-KARS

Ready-to-use Adenovirus expressing Human KARS (lysyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CMTRIB; DFNB89; KARS1; KARS2; KRS; lysine tRNA ligase; lysine--tRNA ligase; lysRS; Lysyl-tRNA synthetase
Description (eCommerce)
KARS is an aminoacyl-tRNA synthetase that functions to charge tRNAs with their cognate amino acids.
Description (Vector)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3735
Gene Name (eCommerce)
lysyl-tRNA synthetase
Gene Name (Vector)
lysyl-tRNA synthetase
Gene Symbol
KARS
HGNC ID
HGNC:6215
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
Protein Name (eCommerce)
Lysine--tRNA ligase
RefSeq ID
NM_005548
RefSeq Synonyms
NM_005548, NM_001130089, BC004132,
Research Areas
Cytoskeleton,Gene Expression,Host-Virus Interactions,Mitochondrion,Neurobiology,Neurodegeneration,Neurodevelopment,RNA Processing,Translational Control,tRNA Binding
Research Areas (Faceted)
cell_biology,developmental_biology,genetics,infectious_disease,neurobiology,transcription_translation
Species
human
Target Sentence
KARS is an aminoacyl-tRNA synthetase that functions to charge tRNAs with their cognate amino acids.
UniGene ID
Hs.3100
UniProt ID (eCommerce)
Q15046

Recently Viewed Products

AAV-h-SPATA18

Cat No: AAV-224102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.