human ISCU Adenovirus
This is an Adenovirus expressing Human ISCU.
ADV-212433
Ad-h-ISCU
Ready-to-use Adenovirus expressing Human ISCU (iron-sulfur cluster assembly enzyme). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310020H20Rik; HML; hnifU; ISU2; NIFU; NIFUN
Description (Vector)
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
Gene ID
23479
Gene Name (Vector)
iron-sulfur cluster assembly enzyme
Gene Symbol
ISCU
HGNC ID
HGNC:29882
ORF Size (aa)
504
RefSeq ID
NM_014301
RefSeq Synonyms
NM_213595, NM_014301, NM_001320042, NM_001301141, NM_001301140, BC061903, BC011906,
Species
human
UniGene ID
Hs.711414
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.