human IRAK1 Adenovirus

Name 
Ad-h-IRAK1
Cat No 
ADV-212390
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IRAK1.

ADV-212390
Ad-h-IRAK1

Ready-to-use Adenovirus expressing Human IRAK1 (interleukin 1 receptor associated kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
interleukin-1 receptor-associated kinase 1; IRAK; IRAK-1; pelle; Pelle homolog
Description (eCommerce)
Interleukin-1 receptor-associated kinase 1 (IRAK1) is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B [taken from NCBI Entrez Gene (Gene ID: 3654)].
Description (Vector)
IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3654
Gene Name (eCommerce)
interleukin 1 receptor associated kinase 1
Gene Name (Vector)
interleukin 1 receptor associated kinase 1
Gene Symbol
IRAK1
HGNC ID
HGNC:6112
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1902
ORF Size (bp)
1902 bp
Protein Name (eCommerce)
Interleukin-1 receptor-associated kinase 1
RefSeq ID
NM_001569
RefSeq Synonyms
NM_001569, NM_001025243, NM_001025242, BC054000, BC014963,
Research Areas
Apoptosis,Cytokine Signaling,EPO Signaling,Host-Virus Interactions,Immunology,Innate Immunity,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,MAPK Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,Signal Transduction,Toll-like Receptor Signaling,Transcription Factor/Regulator,VEGF Signaling
Research Areas (Faceted)
cell_biology,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Interleukin-1 receptor-associated kinase 1 (IRAK1) is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B [taken from NCBI Entrez Gene (Gene ID: 3654)].
UniGene ID
Hs.522819
UniProt ID (eCommerce)
P51617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.