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human INTS3 Adenovirus

Name 
Ad-h-INTS3
Cat No 
ADV-212318
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human INTS3.

ADV-212318
Ad-h-INTS3

Ready-to-use Adenovirus expressing Human INTS3 (integrator complex subunit 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C1orf193; C1orf60; INT3; integrator complex subunit 3; sensor of single-strand DNA complex subunit A; sensor of ssDNA subunit A; SOSS complex subunit A; SOSSA; SOSS-A
Description (eCommerce)
Integrator complex subunit 3 (Int3) is a subunit of the integrator complex which associates with the C-terminal domain of the RNA polymerase II large subunit involved in the processing of small nuclear RNAs U1.
Description (Vector)
INTS3 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)). INTS3 is also a subunit of single-stranded DNA (ssDNA)-binding complexes involved in the maintenance of genome stability (Huang et al., 2009) (PubMed 19683501).(supplied by OMIM, Feb 2010)
Gene ID
65123
Gene Name (eCommerce)
integrator complex subunit 3
Gene Name (Vector)
integrator complex subunit 3
Gene Symbol
INTS3
HGNC ID
HGNC:26153
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3129
ORF Size (bp)
3129 bp
Protein Name (eCommerce)
Integrator complex subunit 3
RefSeq ID
NM_023015
RefSeq Synonyms
NM_023015, NM_001324475, BC116458, BC105094, BC105092,
Research Areas
Cell Cycle,DNA Damage/Repair,RNA Processing
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Integrator complex subunit 3 (Int3) is a subunit of the integrator complex which associates with the C-terminal domain of the RNA polymerase II large subunit involved in the processing of small nuclear RNAs U1.
UniGene ID
Hs.516522
UniProt ID (eCommerce)
Q68E01

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.