human IL9 Adenovirus

Name 
Ad-h-IL9
Cat No 
ADV-212216
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL9.

ADV-212216
Ad-h-IL9

Ready-to-use Adenovirus expressing Human IL9 (interleukin 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cytokine P40;homolog of mouse T cell and mast cell growth factor 40;HP40;IL-9;interleukin-9;P40;p40 cytokine;p40 T-cell and mast cell growth factor;T-cell growth factor p40
Description (eCommerce)
Interleukin 9 is a multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. IL-9 induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, IL9 exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK - STAT pathways. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P15248].
Description (Vector)
IL9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Gene ID
3578
Gene Name (eCommerce)
interleukin 9
Gene Name (Vector)
interleukin 9
Gene Symbol
IL9
HGNC ID
HGNC:6029
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
435
Protein Name (eCommerce)
Interleukin-9
RefSeq ID
NM_000590
RefSeq Synonyms
NM_000590, BC066287, BC066286, BC066285, BC066284, BC066283,
Research Areas (Faceted)
immunology,signal_transduction
Species
human
Target Sentence
Interleukin 9 is a multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. IL-9 induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, IL9 exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK - STAT pathways. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P15248].
UniGene ID
Hs.960
UniProt ID (eCommerce)
P15248

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.