human IL10RA Adenovirus
This is an Adenovirus expressing Human IL10RA.
ADV-212023
Ad-h-IL10RA
Ready-to-use Adenovirus expressing Human IL10RA (interleukin 10 receptor subunit alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R
Description (Vector)
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Gene ID
3587
Gene Name (Vector)
interleukin 10 receptor subunit alpha
Gene Symbol
IL10RA
HGNC ID
HGNC:5964
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_001558
RefSeq Synonyms
NM_001558, BC028082,
Species
human
UniGene ID
Hs.504035
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.