human IDH3G Adenovirus

Name
Ad-h-IDH3G

Cat No
ADV-211775

Availability
4-5 weeks

This is an Adenovirus expressing Human IDH3G.

ADV-211775

Ad-h-IDH3G

Ready-to-use Adenovirus expressing Human IDH3G (isocitrate dehydrogenase 3 (NAD(+)) gamma). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

H-IDHG

Description (Vector)

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Gene ID

3421

Gene Name (Vector)

isocitrate dehydrogenase 3 (NAD(+)) gamma

Gene Symbol

IDH3G

HGNC ID

HGNC:5386

ORF Size (aa)

1182

ORF Size (bp)

1182 bp

RefSeq ID

NM_174869

RefSeq Synonyms

NM_174869, NM_004135, BC001902, BC000933,

Species

human

UniGene ID

Hs.410197

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.