human HOXD10 Adenovirus

Name
Ad-h-HOXD10

Cat No
ADV-211471

Availability
4-5 weeks

This is an Adenovirus expressing Human HOXD10.

ADV-211471

Ad-h-HOXD10

Ready-to-use Adenovirus expressing Human HOXD10 (homeobox D10). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Hox-4.4; HOX4; HOX4D; HOX4E

Description (Vector)

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Gene ID

3236

Gene Name (Vector)

homeobox D10

Gene Symbol

HOXD10

HGNC ID

HGNC:5133

ORF Size (aa)

1023

ORF Size (bp)

1023 bp

RefSeq ID

NM_002148

RefSeq Synonyms

NM_002148, BC074760, BC069619,

Species

human

UniGene ID

Hs.123070

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.