human HFE Adenovirus

Name 
Ad-h-HFE
Cat No 
ADV-210991
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HFE.

ADV-210991
Ad-h-HFE

Ready-to-use Adenovirus expressing Human HFE (hemochromatosis). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HFE1; HH; HLA-H; MVCD7; TFQTL2
Description (Vector)
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Gene ID
3077
Gene Name (Vector)
hemochromatosis
Gene Symbol
HFE
HGNC ID
HGNC:4886
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
RefSeq ID
NM_000410
RefSeq Synonyms
NM_139011, NM_139010, NM_139009, NM_139008, NM_139007, NM_139006, NM_139004, NM_139003, NM_001300749, NM_000410, BC117203, BC117201, BC074721,
Species
human
UniGene ID
Hs.233325

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.