human GYPB Adenovirus

Name 
Ad-h-GYPB
Cat No 
ADV-210705
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GYPB.

ADV-210705
Ad-h-GYPB

Ready-to-use Adenovirus expressing Human GYPB (glycophorin B (MNS blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD235b; GPB; GYP; MNS; PAS-3; SS
Description (Vector)
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB.
Gene ID
2994
Gene Name (Vector)
glycophorin B (MNS blood group)
Gene Symbol
GYPB
HGNC ID
HGNC:4703
ORF Size (aa)
276
RefSeq ID
NM_002100
RefSeq Synonyms
NM_002100, NM_001304382, BC121078, BC121077, BC069310,
Species
human
UniGene ID
Hs.654368

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.