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human GSTM5 Adenovirus

Name 
Ad-h-GSTM5
Cat No 
ADV-210611
Availability
4-5 weeks

This is an Adenovirus expressing Human GSTM5.

ADV-210611
Ad-h-GSTM5

Ready-to-use Adenovirus expressing Human GSTM5 (glutathione S-transferase mu 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GSTM5-5; GTM5
Description (Vector)
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Gene ID
2949
Gene Name (Vector)
glutathione S-transferase mu 5
Gene Symbol
GSTM5
HGNC ID
HGNC:4637
ORF Size (aa)
657
ORF Size (bp)
657 bp
RefSeq ID
NM_000851
RefSeq Synonyms
NM_000851, BC058881,
Species
human
UniGene ID
Hs.75652

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.