human GSTA4 Adenovirus

Name
Ad-h-GSTA4

Cat No
ADV-210595

Availability
4-5 weeks

This is an Adenovirus expressing Human GSTA4.

ADV-210595

Ad-h-GSTA4

Ready-to-use Adenovirus expressing Human GSTA4 (glutathione S-transferase alpha 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GSTA4-4; GTA4

Description (Vector)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.

Gene ID

2941

Gene Name (Vector)

glutathione S-transferase alpha 4

Gene Symbol

GSTA4

HGNC ID

HGNC:4629

ORF Size (aa)

390

RefSeq ID

NM_001512

RefSeq Synonyms

NM_001512, BC063439, BC015523,

Species

human

UniGene ID

Hs.485557

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.