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human GPNMB Adenovirus

Name 
Ad-h-GPNMB
Cat No 
ADV-210248
Availability
4-5 weeks

This is an Adenovirus expressing Human GPNMB.

ADV-210248
Ad-h-GPNMB

Ready-to-use Adenovirus expressing Human GPNMB (glycoprotein nmb). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HGFIN; NMB
Description (Vector)
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10457
Gene Name (Vector)
glycoprotein nmb
Gene Symbol
GPNMB
HGNC ID
HGNC:4462
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_002510
RefSeq Synonyms
NM_002510, NM_001005340, BC032783,
Species
human
UniGene ID
Hs.190495

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.