human GOPC Adenovirus

Name
Ad-h-GOPC

Cat No
ADV-210175

Availability
4-5 weeks

This is an Adenovirus expressing Human GOPC.

ADV-210175

Ad-h-GOPC

Ready-to-use Adenovirus expressing Human GOPC (golgi associated PDZ and coiled-coil motif containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CAL; CFTR-associated ligand; dJ94G16.2; dJ94G16.2 PIST; FIG; fused in glioblastoma; golgi-associated PDZ and coiled-coil motif containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; GOPC1; PDZ protein interacting specifically with TC10; PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10; PIST

Description (eCommerce)

CFTR-associated ligand (CAL) plays a role in intracellular protein trafficking and degradation. Cal may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. CAL may also regulate the intracellular trafficking of the ADR1B receptor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HD26].

Description (Vector)

GOPC encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

57120

Gene Name (eCommerce)

golgi associated PDZ and coiled-coil motif containing

Gene Name (Vector)

golgi associated PDZ and coiled-coil motif containing

Gene Symbol

GOPC

HGNC ID

HGNC:17643

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1365

ORF Size (bp)

1365 bp

Protein Name (eCommerce)

Golgi-associated PDZ and coiled-coil motif-containing protein

RefSeq ID

NM_020399

RefSeq Synonyms

NM_020399, NM_001017408, BC009553,

Research Areas

Golgi Apparatus,Neurobiology,Synapse,Transport

Research Areas (Faceted)

cell_biology,neurobiology

Species

human

Target Sentence

CFTR-associated ligand (CAL) plays a role in intracellular protein trafficking and degradation. Cal may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. CAL may also regulate the intracellular trafficking of the ADR1B receptor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HD26].

UniGene ID

Hs.191539

UniProt ID (eCommerce)

Q9HD26

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.