Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FXN

Gene Name

frataxin

Gene ID

2395

Gene Synonyms

CyaY; FA; FARR; FRDA; X25

ORF Size

633 bp

RefSeq#

BC023633

Gene Description

This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.29978

HGNC ID

HGNC:3951